Both are worth a playthrough imho, but Wasteland 2 is far better.
Wasteland 2 is, especially with the directors cut, a really fun mix between Fallout 1 and a regular combat oriented turn based game. Its a bit more linear and structured as fallout, but then again its also a much longer game, and you could even say that different parts of the game offer a similar nonlinear approach as the original Fallout did. Also there is less replay value despite offering the same kind of differing questsolutions because as you lead a whole squad, you can pretty much specialize in all important skill in one playthrough, whereas in fallout you cant play the jack of all trades and expect to succeed at everything. The writing is comparable to Fallout 2, over the top trash movie charme like mad max with lots of (dark) humour which is kinda a hit and miss. Still its much better than i expected when i started the game up because of all that ranting of fellow codexians. I also really like the fact that you can mess up in this game by simply saying the wrong things at the wrong time or siding blindly with the next best faction you come across.
Seriously, play that game. Its imho one of the best in recent years.
POE on the other hand is... yeah its Baldurs Gate minus the epic demigod plot and instead with some low key philosophical plot about souls that drifts off into esoterical drivel at times. It tries to be Planescape Torment without reaching its excellence by far ofcourse, and it has its weaknesses both in combat (much meaningless trash encounters, faulty AI) and writing (occasional infodump overload, backernpcs) but it definitely also has its strengths. The locations are beautiful and well thought through, it has alot of atmosphere, there are some interesting encounters, questdesign is mostly good to really good, interesting reputation system, mostly interesting companions and IMHO a well designed fantasy world with some interesting background twists.
You will hear alot of hate about the game here on codex, because many people here backed the game and waited for it for a looong time having wet dreams about it every night only to find out that its "just" another Baldurs Gate clone. Its about as good as the first part of the series, nowhere near as good as the second one. Hopefully POE2 will be better.