Handgun statistics say, that the target generally goes down in less than two hits, no matter the caliber. But they also say, that it is hard to hit someone with a handgun if they aren't in your face.
With the introduction of the M16, an often heard complaint was: "Those drugged Vietnamese keep on coming after you pump them full of lead! This gun sucks!" Of course, that is more a question of inertia and time going very fast during a gunfight. That target is going down. It was just, that the previous .30 guns made a big mess out of everything they hit. It was instantly clear that the target wasn't human anymore. The M16 made it much easier to hit that target on full auto, but it wasn't as spectacular.
That same complaint is often heard about any gun that makes it easy to hit a target with many bullets. The bullets have to be small and fast, so it isn't immediately apparent that something happened. Especially with armor-piercing bullets, as those make small holes. If you make it easy to hit that target, that doesn't mean that you have to hit it more often before something happens. It mostly means, that it is easy to hit that target many times before something happens.
If it is hard to hit something, but the result is spectacular, people will think it is a great gun: "He just, Exploded!". But actually it is a really crappy gun. The easier it is to hit, the better the gun. Any hit will have a severe impact.
Then again, this is all considering that the average distance in most gunfights is less than 50 meters. 100 meters is far. And if you go beyond that, you want a semi-automatic rifle, with a scope. Aim before firing. At that distance, hosing the target down isn't going to work. Or a handgun.