MOBA's, all of them really.
Paradox games, nothing against them, just seem too time consuming and while i don't mind looking at stats, it feels like looking at too many spreadsheets and numbers in a way that makes 4X games look like fast paced frenetic games, i also don't think i am as interested in spreadsheet historical fiction as many people, i don't mind it in RPG's, many other games and books/TV/movies, but even looking at some insane screenshots of Crusader Kings and stories from people for some reason don't make me want to try the games at all.
Collectible Card Games, look, some card games are quite fun, but they don't revolve around hundreds to thousands of cards where you buy packs and those with money get all the best stuff, i will try some card games, i will not try Magic The Gathering:Arena or Hearthstone.
Jumpscare Horror games, Survival Horror is fine, but when it's just a game where you walk around until something screams at you, i have no interest in it.
Going by genre, there are some individual games or series i am not into but i went just on a big scale...fine:
Dark Souls and the other Soulsborne games after 1, i tried playing the first Dark Souls, i really tried just to see what the hype was around, it just felt like a slow action game that spread somethings to pretend to have deep lore, cool that it's aimless and you can explore and get to a bad area easily, but i think i like my action games to be generally faster and if you consider it a RPG...then with more characters to interact with and more stuff to do.
I just really didn't get into Dark Souls, i did die though, but it's one of those games where generally knowing what is ahead will make you live, and after a while i could go through many encounters first try.
Not the worst thing ever, but it made me not really look into more games in the franchise and make me ponder what the hell Dark Souls 1 has that made so many people crazy for it that i didn't get.