The thing I remember about Point Lookout is how ridiculously overpowered those rednecks were. Accurate as fucking Simo Häyhä, heavy hitting and bullet spongy. One of the most toughest enemies in the entire Fagout 3, no doubt. Who would think that the inbred and mutated southern Americans would be way more dangerous than Enclave or supermuties?
Pretty fun story actually.
One of major complaints (aside from story, Little Lamplight, butchering of lore, etc) was the difficulty. You could sneeze at a raider and his head would explode.
Guys at Bethesda thought a bit and came up with 2 solutions that they implemented in 2 DLCs.
One was bullet sponges- implemented in Broken Steel. Special variants of common enemies spawn after you reach DLC levels- 20+.
How spongy are they? (All data from Fallout Wiki):
Ghoul HP: 25
Ghoul Reaver HP: 1100
Radscorpion: 150
Albino Radscorpion: 1500
Supermutant: 100
Supermutant Overlord: 1250
Second option was increasing their damage. But what happens when player gets their hands on those powerful toys?
So some genius implemented in Point Lookout extra special damage that ignores completely your armour rating and is applied per bullet hit.
And then another genius added a double barrel shotgun, that shoots 14 pellets per shot (each pellet has this effect applied).