I think it would be of benefit to everyone here and most importantly Cleveland Mark Blakemore to know of these things so that they can be resolved hopefully in a future update to Grimoire. Please feel free to contribute with your own conformations that these are present for you as well, or list any other defects you have discovered. I will try to keep this OP up to date as information and feedback becomes more available.
Description: Dead characters can and will continue shielding allies.
Reproduce: Choose the shield option for a character and have him shield the party member alongside him (not himself). Let the shielder die while performing this action in combat. For the remainder of combat, you should see that when the formerly shielded character is attacked, the text will still report that he is being shielded by the dead shielder.
Description: 2 Handed access is greyed out after unequipping.
Reproduce: Equip a 2handed weapon on a character, the offhand will be greyed out correctly. Unequip the 2handed weapon, and the offhand will remain greyed out. In order to make it non greyed out again, you have to equip a 1handed weapon first.
Description: Item enhancements are lost after dropping them.
Reproduce: Craft on an item with one of the enhancements such as poison or sharp. Drop it on the ground from your inventory. Now pick it up again, and the item enhancement will be gone.
Description: Magic missile, possibly other spells, target multiple contrary to spell descriptions.
Reproduce: Cast magic missile in combat, it will attempt to deal damage to multiple targets in the row, despite its description saying that it only affects one target. I haven't confirmed what other spells this may be affecting.
Update: The in game description for magic missile is actually incorrect, and the spell is correctly supposed to affect multiple targets.
Description: Map footnote text is part of the save file text.
Reproduce: Make some map footnotes, anywhere on whatever maps. Save your game. The save file will append the footnote text to the party name spot. E.G. if your party name is "The Beatles", and you put a footnote on a map saying "Locked chest", after saving it's likely that you will see the save text on the party name line as "The Beatles Locked chest".
Description: Smooth turning contains graphical artifacts.
Reproduce: Turn left/right in game with smooth turning enabled and a wall to your left/right/front. If you are next to a wall, you will be able to see that wall turn with you as a graphical artifact being carried through your turn.
Description: Text in the journal descriptions get cut off if it goes too far right or has too many lines.
Reproduce: Find descriptions in the journal that contain too many lines or go too far right for a line and the words will get cut off.
Description: Megalith Spire shortcut causes skyboxes to vanish.
Reproduce: In the Megalith Spire, walk through the hole in the floor that transports you back to the Bahomet Megalith floor 1, and then exit the building to go outside. The skyboxes will be gone and replaced with a solid blue color, even when then transitioning areas. To avoid this, walk back the long way down the tower that you came up to go back outside and the skyboxes will be normal. AVOID THE MEGALITH SPIRE SHORTCUT!
Description: Incorrect graphic on the map for ladder between prophecy pitfall and the garden above it. The ladder shown in the image where my party is on indicates that the ladder travels downward, but that ladder actually connects to the garden ABOVE it, so it should instead have an arrow pointing up like the rest of the ladder icons on the map.
Reproduce: See map for prophecy pitfall and how it connects to the garden above it.