plague/pandemics in games

[Martyr]

games that feature the/a plague/a pandemic that I know of:

Deus Ex - Gray Death (cyberpunk stealth with RPG elements)

Neverwinter Nights - Wailing Death (Bioware RPG)

Greedfall - Malichor (action-RPG & cutscene simulator)

Dishonored - Rat Plague (steampunk stealth)

A Plague Tale - haven't played it, but I know it's the central theme (fantasy stealth)

Patrician & Anno series - plague (trading management & city builder)

Penumbra: Black Plague - haven't played it yet (horror adventure/stealth)

Entomorph: Plague of the Darkfall - a "plague" that turns people into insects ... (action game/RPG)

what else is there?

 

[CruduxCruo]

The Witcher - The Catriona plague

 

[Manjuice Nutella]

Metal Gear Solid V, and it's even a man-made virus attacking lungs engineered in a third world shithole

EDIT: Also Red Dead Redemption 2:

Spoiler

Arthur contracts Tuberculosis before penicillin was invented, and is literally COOFING all the time

 

[Wunderbar]

Pathologic

 

[Aemar]

Stellar Tactics - Phage outbreak (turns humans into zombie-like creatures)

Plague Inc. - THE game about pandemics, etc.

Crusader Kings 2 - black plague and all that medieval good stuff

Guild 2 Renaissance - black plague

 

[CryptRat]

In Lurking II: A Madness you're fighting against "The Madness" which is spreading around people of the world as you play. Recently infected characters would randomly get red eyes and deliver some dark message instead of answering what you're asking for, until their eyes eventually stay red and you can't get any info from them anymore.

 

[olgar]

Metro Last Light - Ebola virus

 

[Infinitron]

Penumbra: Black Plague - haven't played it yet (horror adventure/stealth)

lol. There isn't really a plague in Penumbra: Black Plague.

Spoiler

the title is referring to an alien possession/zombification scenario in an isolated compound in Greenland

 

[laclongquan]

Sengoku Rance~ An much important part of the game happened alongside plague.

 

[zapotec]

What about Morrowind and the blight?

 

[GewuerzKahn]

Nier - Black Scrawl

Spoiler

It's nooot really a virus. I know.

Mass Effect 2 - Plague in Omega

Virtue's Last Resort - Radical-6

 

[Kalin]

Alpha Centauri - Prometheus virus and genetic warfare

 

[DalekFlay]

Dishonored - Rat Plague (steampunk stealth)

So well done too. That level where you see where they're dumping the bodies, and people exiled there are all around... great stuff. Dishonored 2 is a great game as well but the insect invasion or whatever is nowhere near as good.

 

[Alphons]

HITMAN Patient Zero- Doomsday Virus

 

[PeachPlumage]

Neo Scavenger - Blue Rot

 

[laclongquan]

Parasite Eve 1 and 2. Much of the game happened around super virus mutating animals, plants, and humans.

 

[Mr. Pink]

Neo Scavenger - Blue Rot

The most realistic social distancing simulator I've ever played. Come within six feet of anyone and you're dead.

 

[Jokzore]

Every Resident Evil and every zombie game ever.

 

[DDZ]

Plague Inc.

Edit: I'm blind and I thought somehow everyone missed the obvious.

 

[Martyr]

I've also found another game - Reign: Conflict of Nations - a russian grand strategy game which looks quite similar to Crusader Kings. the setting is eastern european instead of central european. it starts off in 1350, so in the midst of the Black Death.

 

[Taka-Haradin puolipeikko]

Warcraft 3 human campaign.

 

[Martyr]

Vampyr (2018 ARPG by Dontnod) - Spanish Flu

 

[Semiurge]

Mortis....

 

[rusty_shackleford]

the division, I only played it for a bit but I assume it was the entire plot

 

[Norfleet]

World of Warcrap, the blood corruption one. Not just some plot point, but an actual plague that even the CDC found interesting.