Just played 3 hours. Some thoughts...
1. It looks blurry on ultra as someone said above, but if you turn off depth of field (which especially looks awful), chromatic aberration and the blur AA it does not. It's not like you can't change the settings guys. Now, whether you want blur AA or jaggies is your call, but definitely turn off depth of field. It looks fucking awful, with things blurring everywhere even pretty close to the camera while walking around. Can't imagine suffering the console versions that don't let you turn shit like that off.
2. I don't really have any bugs or glitches as someone said above. No sound errors, no jank really. I turned shadows down to high and it runs 60fps locked with v-sync and no resolution downscale on a 1060 at 1200 res, which I am happy with. Only real port issue I have is the default keybinds are ass, but you can change all of them. Oh and the weapon model is too close, making even a 90 FOV feel tight, but that's pretty normal lately for whatever reason. Anyway, the jank is probably PC dependent. It feels "AAA" to me, whatever value that has to you. Oh and you can hit space bar when it says you have to hit enter, FYI. Was annoyed until I realized that.
3. It's basically a Far Cry 3 type of game. Even has outpost type things you clear, and the same kind of upgrade thing. You earn resource points by doing missions and those you use to upgrade certain skills. Other things like weapon upgrades and powers you have to find things in the world that you boost them with. Gunplay feels good, not as solid as Doom 4 (it's a different engine, Avalanche's engine, which I didn't realize) but solid. If you like this type of game and want one in a sci-fi/mad max style settings, I can't imagine why you wouldn't like this one. I'm sure dozens of people in this thread will tell me how horrible it is though.
4. You do need to login to Bethesda account for pre-order items, but who the fuck cares about cheat style pre-order items? I couldn't care less (though Steam automatically logged me in anyway).