Do you want games with strong reactivity, i.e., choices and consequences? Fallout, Fallout 2, Fallout: New Vegas, Arcanum, Planescape: Torment, Prelude to Darkness, King of the Dragon Pass, Darklands, Never Winter Nights 2: Mask of the Betrayer, Knights of The Old Republic 2, Vampire the Masquerade: Bloodlines and Dragon Age: Origins. Please notice that this list is a mixed bag. Some of these games are great while others are just ok. Some games have deep reactivity with skill checks and multiple endings, while others have pockets of reactivity in side quests, few skill checks and linear story. Some of these games are isometric, while others use a FPS engine. Some of these games have good writing and good story, or good atmosphere and art direction, while others not so much. FO and FO2 are two of the main inspirations of AoD.
Other games that I don’t like, but have lots of reactivity are Alpha Protocol, Baldur’s Gate 2, Never Winter Nights 2, Wasteland 2, Knights of The Old Republic and Mass Effect. I would not recommend Pillars of Eternity even in this list, because is a shallow game that wants to be perceived as a isometric classic. Underrail is a great game, but most of the quests are linear. The reactivity in this game is mostly on the factions quests.
If you want good combat, you should play strategy games. JA:2 is the best I played. Underrail is one of the few cRPGs that I can say also has good combat.