- Setting: Odyssey is set in classical Greece, which is quite similar to many other games, since much of western fantasy is based on medieval Europe, which is not that different from ancient Greece.
If differences aren't in games it is because of games (obviously including this one) not actual similarities.
I meant in terms of the climate, flora, fauna, etc.
So do I.
First: Ancient Greece in classical era wasn't the same one as today. You need to add western Asia Minor, and
Megálē Hellás - Magna Grecia (southern Italy). Perhaps even all areas of Greek colonisation. OTOH remove Epirus and Macedonia.
Greece has Mediterranean climate, relatively arid and hot, very different than England and Western Europe in general - the one you see in usual fantasy hacks and games. Which means a significantly different type of vegetation, that includes agriculture as well to some extent. Remove significant rivers or large expanses of plains or big areas of forests but add a lot of mountains.
More important than the above, Greece was a culture (and geography) strongly centred around the sea! Sea transport was paramount for most. Do you remember sea mentioned in Tolkien's trilogy (other than Elves leaving middle-earth, once or twice)? No? Because there are like 2 or 3 cases, all in 3rd tome, that's all. Even less (or none?) in Hobbit. Games are based on that. If a game on Greece does not include a lot of sea, sea voyages (like in Odyssey - the original one, pun is intended), sea battles or wars overseas then it is doing it very wrong. And by that reason alone it is in some ways more different than an Egypt setting.
Does the images below look like your imagination tell you Shire, Gondor or Mirkwood should look?