Additionally, for those who don't know, Fallout 3/NV/4 having the VATS targeting system is the newschool version of the old Fallout's being turn-based. During your turn, you could either spend your Action Points just shooting at your opponent(s) (in FO3 onward, this is the equivalent of "real time" combat) or spend more AP targeting specific body parts (in FO3 onward, this is the equivalent of VATS targeting). Eye damage lowered enemy accuracy, arm damage affected enemy two-handed weapon ability, leg damage caused enemies to expend more of their AP in per-tile movement, etc. Effective headshots were higher damage, and groin shots were always hilarious.