I've been pondering if trying GDMX for first playthrough, but in the end I went vanilla.
I appreciate the other stuff made by Ash (in particular, the unreal mod), but there is a certain guy on reddit that has made some cool posts explaining why he doesn't recommend GMDX to first time players, in addition to noting why he thinks it isn't as lore-friendly and after reading him, I'm thinking I've made the right choice.
The user name on reddit reviewing this mod is
YCCCM7, and he has also experienced older versions of GMDX:
https://www.reddit.com/r/Deusex/com...=web3xcss&utm_term=1&utm_content=share_button
I will post some cool links about why he doesn't agree with GMDX philosophy:
1) why the mod should be mostly recommended to second time players, and not as first choice for first time players:
https://www.reddit.com/r/Deusex/comments/mcjc7r/comment/gs8a461/
I will add my own consideration: the mechanic above is absolutely required for first time player; more than once I had issues with lockpick and nano being so slim even if I searched whole map. As a new player, I had no nano and lockpicks (wasted all of them) and was actually able to get in the warehouse basement in the beginning of the game (the one you're sent by Paul to investigate at game's beginning) and succeed only because there were failsafes in the form of TNT readily available to be used.
1.1) Consequences of the above:
https://www.reddit.com/r/Deusex/comments/kucy14/comment/giw9m48/
https://www.reddit.com/r/Deusex/comments/faa5ue/comment/fixn3h0/
2) why the mod isn't lore friendly:
https://www.reddit.com/r/Deusex/com...=web3xcss&utm_term=1&utm_content=share_button
There are some other cool nitbits if you take a look at his profile page. Good reading.
TLDR: don't play GMDX if you're a first time player. Go for Deus ex
Trascendent for your first playthrough.