Is it time to jump in boys?
For story reasons, is it best to play a custom char and recruit compas vs playing their role yourself?
There is nothing special about companions. You will be part of their origin quest even if they are no longer alive, you might miss specific quest outcome though.
What is important is to carefully chose tags for PC, which origin characters got locked.
Avoid noble and barbarian. I've played Beast as PC and it was terrible.
Jester is nice(for me mandatory even), Outlaw fits rogues, Scholar unlocks some quests.
Dont know much about Mystic or Soldier, maybe someone else can explore those.
EDIT: at no point origin companions will disagree or whatever. After joining they are mindless puppets and will never turn on you. They will just share pieces of their tragic backstories. If you are choosing origin characters as companions, pick ones that seem interesting for you. Hint: From what I've red no one found Beast interesting, Sebile story gets interesting in a2.