All you really need is to install the game with EE and enjoy. Played it several times with just base EE. Don't listen to these contrarian, autistic phaggots with their 10+ mod lists.
I just finished BG2 and that's about right if you just want to go in with as little headache as possible. No particular setup, some QoL, I remember talks about bugs at release but can't say I've encountered any. Unless you're personally invested in not supporting Beamdog, which is fair (I didn't support them either, eh), the EE are what a newcomer should default to. Add ReShade for Sharpen+Levels+Vibrance+CRT and you're set.
The new companions are a drop in the ocean, you can just ignore or blitz them, that's forced outrage if I ever see it; plus honestly just fucking lel at that revisionist take where they are noticeably bad compared to the originals. This is BioWare we're talking about for fuck's sake, you could probably swap Beamdog and BioWare companions to a clueless first-timer and he would be hard-pressed to tell you which is a monocled original and which is a cringe insert between Aerie, Neera, Jan, Dorn or Nalia. Odds are he would think Edwin is obviously a trans pandering Beamdog insert.