The best Sci-Fi fantasy mix, though was in Morrowind.
Wizardry was a bit of a kitchensink in regards to elements used - ultimately cool and very fun but also derpy, kitschy, incoherent mess of random "cool" elements, while in TES you got stuff like steampunk dorfs (who were actually bearded elves), demigod making himself cybernetic interface and experimenting with constructing cyborgs, and artificial life, one of the oldest structures in the lands possibly being built around an ancient spaceship while remaining internally consistent.
True, it's not Sci-Fi, per se, but more like Sci-Fi plausible in given fantasy context.
After that description, I may have to play Morrowind after all.
It's all subtle and in the background, though.
Cyborg stuff is from the first expansion, but the ending is disappointing in terms of implementation. The ideas are there though.
Spaceship thing, I'm not sure if it's actually referenced in games, or only in semi-official, semi-canon of additional texts by MK.
Overall I thoroughly recommend Morrowind as long as:
- you don't expect awesome interactions with interesting characters
- you don't expect good combat
- you can refrain from exploiting obvious loopholes
- you can refrain from looking up game relevant information on the 'net