I would rather see a good bottom-up mini-setting for a change. Something that's relatively light on the big picture (mostly to help players get their bearings, give them a selection of gods to worship and organizations to join), and focused on things which are immediately relevant to playing the game and having adventures. Not necessarily as micro level as the Wilderlands of High Fantasy, which goes down to the encounter level, but something that gives you a self-contained sandbox where you get a few established bases of operation (cities, strongholds, villages, temples; that sort of thing), places where you can get into trouble, a few sample organisations to join forces with or confront, encounter charts, rumours, and a handful of readymade mini-adventures to start with before you start adding your own - with lots of ideas and suggestions for the GM to develop things further. There have been fairly good attempts at creating something reasonably similar, but very few of them have been really good, and none hit all the right notes.
of CRPGs using DnD rulesets in high quality published settings 