The first person I taught to play D&D after I bought the Basic Set in 1987 was my younger sister (we were 13 and 10). She still plays today, as does her daughter (age 12).
I don't get to game too often now, but it's most frequently with husband & wife pairs. Sometimes the wife is actually the longtime player, with the husband tagging along.
Just a couple of weeks ago, I ran a couple of sessions for my wife and our daughters (ages 5 and almost 8). My oldest had been asking me to teach her to play D&D for a few weeks.
They couldn't get enough of the game. The kids anyway.
My wife does enjoy playing though (5e or 1980s Basic; she really didn't like 4e).
My youngest got right into it. I described two goblins emerging from a cave and asked "what do you do?" Without missing a beat, she stood up on her chair and shouted "KILL THEM!!!"
I'm so proud of her.