The game has some meta C&C. If you ever need to work for nobles or royalty but they laugh at you in your face and tell you to get lost, know that it's because you did something for someone who's not in the best mood with that nobilitiy faction, individual noble or royal. Likewise with merchants, taverners etc. Depending on how you play, you might be surprised to find that taverners in some places won't charge you at all.
Also, some guilds have conflicting interests so you can be kicked out from one guild for joining another one, you can be demoted if you turn down or fail too many quests (isn't it nice that you can fail or turn down quests at all and not get stuck in the game?), and if you fail too many quests when you're a low rank in a guild (first 2 or 3 ranks), they can kick you out. Or if your reputation drops below socially acceptable levels, some guilds will either kick you out, or tell you not to come back until you work on your reputation.
Also, some guilds have conflicting interests so you can be kicked out from one guild for joining another one, you can be demoted if you turn down or fail too many quests (isn't it nice that you can fail or turn down quests at all and not get stuck in the game?), and if you fail too many quests when you're a low rank in a guild (first 2 or 3 ranks), they can kick you out. Or if your reputation drops below socially acceptable levels, some guilds will either kick you out, or tell you not to come back until you work on your reputation.