If you feel like going over more of the top 250, I would definitely be interested. No pressure, though. I won't be revisiting FONV for a long time.
Well, let's see:
21. The Someguy Series: I simply think this guy's mods aren't good. People seem to vastly disagree.
22. A World of Pain: this one is a complete mess when it comes to balance, logic, performance, polish, and compatibility.
23. Unlimited Companions: outdated and known to be buggy.
27. 4GB Fallout New Vegas: outdated (use the 4GB patcher on the OP instead).
28. MTUI: Vanilla UI Plus is much better.
29. New Vegas Bounties II: more Someguy mods that are bad.
31. Electro-City: buggy, unpolished, and not something you want to uninstall mid playthrough. Simple Street Lights is better. But I prefer no street lights mod, it's just weird.
33. Pip-Boy Readius: doesn't fit Fallout.
35. Beauty Pack Project Mikoto: terrible, terrible, terrible.
36. Weapons of the New Millenia: somewhat unbalanced, but my biggest issue is that the extremely high quality weapons clash too much with the vanilla ones.
38. Bouncing Natural Breasts: the bouncing looks bad.
39. Mission Mojave: stay away from this. I suspect the people who constantly complain about FNV's stability use this mod instead of YUP. Probably running it in combination with A World of Pain as well.
42. Unified HUD Project: outdated (use User Interface Organizer instead).
44. Project Nevada - Extra Options: it requires the worst modules of Project Nevada to be installed before you can install this... a shame.
Note: Type3 Body and Armor Replacer (plus its DLC add-ons) and Robert's Bodies are pretty good mods that I didn't list because Codexers would make fun of me.
46. FNV Sexual Innuendo: just... no. Sex animations are terrible, plus you run into compatibility issues.
47. Roleplayers Alternative Start New Vegas: this is personal opinion, but I never liked alternate start mods in any RPG.
48. Fallout New Vegas ArchiveInvalidation Invalidated: outdated, MO2 takes care of that.
50. CONELRAD 640-1240 - Civil Defense Radio: this fits Fallout 3 much better than it does New Vegas.
51. Sprint Mod: any sane person should play with JSawyer Ultimate, which already includes a sprinting feature.
52. Wasteland clothing Hires retexture: I don't play with texture mods, broadly speaking.
53. Fellout: Clarity and Realistic Wasteland Lighting are better alternatives.
54. The Inheritance: Someguy, yawn.
56. Fallout - New California: a massive joke.
58. Classic Fallout Weapons - New Vegas: I saw one Codexer recommend this mod once. This is the diametrical opposite to Weapons of the New Millenia: people, somehow, made weapons that looked far worse than vanilla New Vegas'.
59. Underground Hideout New Vegas V4-4: this is my fault, as I don't use house mods, but it is the most endorsed so it has to be good. Right?
60. Monster Mod: doesn't fit Fallout at all.
And it goes on and on. The big issue here is that I don't have my mod list handy to publish to give you an idea as to what I consider to be good mods. Of New Vegas' 20,000 mods, I would play with about 500, but you get the plugin limit far too quickly (not to mention incompatibilities), so I have to sacrifice my setup down to 200 mods or so (since you can still merge the simpler plugins).