Anthony Davis said:
4 humans, fighter, cleric, wizard, and thief. That is all you need.
I haven't done it recently, but I surely did it 'back in the day'...except for pools of darkness, I never played that one.
If you haven't played PoD, your advice is worthless. PoD takes pain to a whole new level. It makes the first three games look like panzy shit.
That having been said, I started a run through the last three games about a year ago that I put down and haven't finished. I started with Curse because I needed Rangers to make the whole thing work. My classes were as follows:
3 Human Rangers
2 Human Clerics
1 Human Mage
Around level 25 - 30 I would then begin dual classing them in PoD in a staggered fashion to:
3 Human Rangers/Mages
2 Human Clerics/Mages
1 Human Mage/Cleric
The reason for this is simple: The last sequence of three battles in PoD are nearly impossible to beat. You want to know what it's like to fight 20 Bits O' Moander along with 20 Dracolichs at the same time? Well thats the first battle. The next battle are about 20 of the undead beholders (the exact name of which escape me at the moment). The final battle (which I've only made it to once and that was pure dumb luck) is the actual final guy along with his demon minions.
Having a lot of high level mage spells at your disposal is a must here. The Rangers are important because as best as I could tell from the manuals, the Ranger is the only class that can dual over to a Mage and still be able to cast all of the spells while holding a sword and a shield. Yet another dumbass 2nd edition rule (much like the horrible gimping of all demi-human races).
I made it through Curse and got to the very end of Secret of the Silver Blades (right outside the final castle). I've just never gone back. Mostly because Secret of the Silver Blades is a really shitty game. PoD is actually one of the best Goldbox games out there, but it is also one of the hardest. There are tons of insane high level D&D battles scattered throughout the game. It reminds of the insanity present within BG2: ToB in a way.
Anyway for those of you who haven't played PoD, I highly recommend it. And if you can beat it, you'll need to back that shit up with some screenshots. The only FAQ for PoD on Gamefaqs pretty much says this in regards to the final battles:
"Turn the difficultly down to easy and pray"
Or something like that.