I played through Struggle for Freedom to basically the very end. I didn't use the custom job boards because modders get a little too arrogant with their bullshit. It had been awhile since I last played vanilla FF12 so I went with the original (but expanded) license boards. Kept my characters pretty specific and focused on their gear until endgame when LP typically becomes useless (my main reason for doing so).
Basch - Swords, Spears, Axes, Heavy Armor, Limited White Magic + Decoy
Vaan - Knives, Ninja Swords, Crossbows, Light Armor
Balthier - Guns, Poles, Heavy Armor, Scales (didnt use)
Fran - Bows, Rods, Magic, Mystic Armor
Ashe - Katanas, Bombs, Crossbows, Magic, Mystic Armor
Penelo - Staves, Greatswords, Mystic Armor, Magic
Covered pretty much all gear, and didn't end up breaking that mold until the end. I killed the Behemoth King until the game got to me. Endgame shit was just too tightly tuned in terms of requiring some RNG. A poorly timed combo would ruin the entire fight and force you to start over because it isn't possible to outheal theor damage with the boosted stats. Gilgamesh was the perfect level of difficulty. Had to change characters frequently, positioning mattered, status effect spamming helped, had to keep an eye on my own buffs. Bubble is MANDATORY for endgame shit. Fought Ultima at the end of Great Crystal, got her down to 1 hit left, Blinded her (Darkga has a passove chance of Blind) and she used Renew for a full heal (yeah, dont Blind her. Lesson learned) and I nearly threw my controller across the room.
Early game is by far the most fun. Fights take a significant amount of time, you need to make liberal use of manual commands for healing, targeting, taking out stronger enemies, etc. It was especially evident in Barheim passage when Basch is a guest, and it did drive home the 'fugitives on the run' vibe at that point.
Some of the hunts required a bit of funky tactics, or waiting until you got a bit stronger. Demon Wall was a close one, but again, use your Motes and you're fine. Brainlessly auto-attacking enemies to death didn't really become a thing until probably I had to go to Archades. But this is from someone who has played the game probably 7 or 8 times at this point, and has most of the Bazaar recipes known pretty well for gear that will overpower you.
Worth playing? First run, no. Every time after that? Yeah, absolutely. I'll leave using modded classes up to you though, I don't like when they fuck with that type of stuff.