Common, the objective of Duke Nukem was to parody those dumb action movies of the 80's for FUN. There was no intention to say anything relevant about women or sexism or any shit like that. There wasn't any message of "You should totally treat all women like hookers.", I really didn't understood the relevance of his comments on Duke Nukem. It looked like he saw some boobies and gone on a pointless critique of sexism on a game that is a parody of the 80's action heroes.
Quake and teen angsts? Well, I aimed at monsters, tried not to die, exploded the monsters and the the monsters died, the end. I really didn't thought on any teen angst at the time. I had fun and that was the only thing I cared. If you changed Quake art style to any other, it won't make any difference to me. I played as a decent FPS of the time and that was about it. Quake is a collection of mechanics and aesthetics (as he said) that don't have much to do with each other, the soundtrack wasn't any different, they just used what was popular at the time. His idea of teen angst and Quake is a nice little observation but making a whole video about it as if it was a dominant theme of the game is just going a little too far.
In Quake, you shoot monsters, monsters die and that is about it, nothing was intended to make sense. I really think his observations are a little off the mark this time. They aren't totally wrong but are way less important than he thinks they are, go watch Super Bunny Hop on youtube and you will see someone that really understands of what the shooters of the time were about. They were about rhythm and movement, the way the enemies fire, the way you fire your guns and the level design all reflect that. Talking about aesthetics on those games is really be superficial as the developers at the time just used random shit they had on their mind at the time (what actually created games full of personality).