I just finished reading the article, and although some statements sound remotely promising (no scalling, dialogues, some other minor stuff that sound like something I might approve of), my general impression was negative. It's a fucking console game, and it shows. Some elements might even be quite good, but it's still *made* for Beth's target audience, which means a lot of annoying shit designed for twitch kiddies, like exploding nuke cars, mutant orcs with warhammers and handheld atomic cannons (wtf?).
Not to mention the "innovative" combat system that offers a compromise of both RT and TB by having the setbacks and weaknesses of both.
Also, when I hear the words "radiant AI" and "Fallout" in one sentence i find really hard to supress the urge to kill someone.
"I saw a deathclaw yesterday", my ass.
However, I see one bright side to this: hopefully the game will be released with a Construction Set, so we'll be able to heavily mod the game, throw out some of the useless/unacceptable crap, change the mechanics if necessary and add some depth to the game (hunger, thirst and whatnot should be easy to implement, for example). Maybe the collective effort of the Fallout fanbase will succeed where Beth fails, and turn F3 into an at least *passable* sequel.