Lemming42
Arcane
Where is it said it came from Fallout 2?
The Vault 8 main computer is the first mention of it I think, where you pass a science check and access some hidden file that details the experiment.
I really doubt they were thinking of it in Fallout 1 since Vault 13 and Vault 15 both worked more or less normally, and Vault 12's shitty door is a believable enough malfunction to not be part of a Grand Sinister Experiment.