Overall, I enjoyed Fallout 4 a lot more than I was expecting. Part of how I rate a game is whether I'm happy or sad when I have to move on to my next review, and with Fallout 4 I'm on the sad side of the ledger. I ran through the game pretty easily on the "normal" difficulty setting -- I could tell I was too powerful when a suicide bomber sneaked up behind me and detonated a mini nuke... and only took off about half my health -- but my character playing on the "survival" setting is having a tougher time, and I'm curious if the game can maintain the challenge all the way through.
In any case, Fallout 4 is in pretty good shape now. The game is stable, the locations are plentiful, and there are numerous interesting quests to complete -- and this is all without a lot of mods being available since Bethesda still hasn't released their construction kit (it's apparently waiting in a "to do" queue along with the manual). So if you like open world RPGs in general, or Bethesda's offerings in particular, then Fallout 4 is a worthwhile game to pick up.