Loading time work arounds
I know this will bring the professionally offended purists nightmares. However, there are mods that allow your party to ignore encumbrance. this is particularly useful in cleaning up the game for better load times. The reason the games load times become more and more atrocious the further you progress, is due in fact, that all the items left on the ground by enemies and opened containers remain cached, to then be loaded back into the world at the place they were dropped. The more enemies you kill, the more you leave behind, the worse your load times will accumulate.
This fortuanantly can be fixed with a bit of proactive work by the player, all you have to do is enable an encumbrance mod upon entering an instanced area and upon exit of its various levels loot everything you left behind. When you get back to the travel map from your adventure, and this is the tedious part, comb your inventory for all the things you do not want to sell and decide to drop them on the world map. this item will be deleted as there is no instance to leave them in, and in turn will free up the cache. You can then just disable the encumbrance mod and travel will affect you as it would have all along.