Skyrim in Space, not Fallout 4 in Space. 45 hours played, "barely scratched the surface." Bug counter: 6 minor ones, 1 broken quest start. Performance stable (~90FPS?) at 1440p Ultra on a 13900KS with a 4090, heavier on the GPU than the CPU.
Main quest at the player's discretion, very freeform, important but not urgent. Side quests "improved." Persuasion is cool, combat is okay-ish, stealth is the usual, lockpicking gets old, enemy AI "surprisingly good" with tactics (except "monumentally dumb about stealth"), remote companion control is gone and they're stupider than enemies. Lots of weapon variety, careful about space suits 'cause Todd likes to automatically kick you out of the ship when you land.
Space flight disappointing, orbit only, the controls are "horrible." No joystick, controller is better than mouse (fuck's sake). Outposts are very different from settlements, very streamlined, you build whole units, they can produce resources and you can squirrel away unwanted companions since your ship has only so much room. Ship building looks cool, but you have viability parameters.
UI is "standard" for Bethesda (lol). The HUD sucks as usual, non-modular, stupid XP and location notices in the middle of the fucking screen.
Conclusion - thoroughly enjoying it, very stable, looks replayable. Mods will fix the rest.