Alright, played Cargo Commander a bit. Seems pretty cool. Quick rundown is you start on your ship which is your central hub, then pull randomly generated cargo containers into it and loot as much as possible before they get sucked into the wormhole. The containers and layout are randomly generated via seeds so you still have valid leaderboards, but they're per-seed (Sector). A sector called RPG Codex Sodomy Circle would always (Or almost always, haven't experimented enough to confirm HOW similar seed replays are) play the same, but naturally it gets increasingly difficult until you either die or end the session manually. As far as I can tell there's no additional penalty for dying, that just ends that particular run and tots up your score.
To get access to new seeds/sectors you need the sector widget. The sector widget will show up relatively early (Probably wave 3-5 I'd say) and seems to generally be in a tougher container. Fewer drillable bulkheads, more enemies, etc. So long as you grab the widget and get back to your home base you'll unlock the ability to generate/add a seed/sector to your list. I'm not entirely sure why they bothered with that, but supposedly each sector only has 6 types of cargo each, so if you're trying to collect every type of cargo (Finding new cargo types seems to net the most XP) I guess they want you jumping around.
Apart from just score attack (Which I'm a sucker for score attack so they've got my number already) there's a persistent leveling system. From what I've seen the two MAJOR upgrades are your first two level-ups which you'll get pretty quickly, first one popped for me after finishing the tutorial. By the way, if you buy the game and you reach the stage where it says "End your work day, or continue for higher score", just end your work day. It's not tracking score during that tutorial from what I see. Anyway, first level-up gets you access to the upgrade bench and allows you to find the game's upgrade currency (HATS!) while you're exploring. Upgrades bought via the bench last for one full game and have your normal better guns, faster movement, more HP, more oxygen, faster drilling type things. Nothing really exciting but it gives you some ability to tailor your playstyle. If RPG Codex Sodomy Circle has particularly rough enemies you may want to upgrade your weapons over your platforming/exploration abilities.
So there you have it. It's not NEARLY as immediately brutal as Spelunky and doesn't seem as well designed on the whole, but that's not to say it's bad. Especially for a randomly generated action platformer. Keeping in mind these are my impressions after about an hour of running around.
Speaking of Spelunky, god damn why isn't the fancy Spelunky remake on Steam? I'm not that crazy about the new graphics for it but still, Spelunky!
Edit: Fuck, just realized I forgot bones levels. Bones levels are in Cargo Commander. If you're playing a sector that other players have, you can find their corpses and loot them for ammo and hats. Here's a picture of a bunch of corpses for no goddamn reason in an easy room. I have no idea why they died there.
http://cloud-2.steampowered.com/ugc/920118814733650994/CB732DBB37F879C9F09EBE1E9214612462BDFFA4/
Edit 2: Hahaha. Was playing a bit more, exploring containers, going swimmingly, and then I launched myself into THIS:
http://cloud.steampowered.com/ugc/920118814735158705/A7BD39DABC54B5ABC2551CBE8960494E347B58CC/
And promptly got my ass kicked. And that's after I sprayed wildly with my best gun and smashed a few monster spawners. That container and specifically where I entered was jam-packed with monsters, but what really made it amusing was all the corpses of other players in that room. Apparently a bunch of other people got caught with their pants down in there.
Edit 3: Made sector RPGCodex. COME FIGHT ME!
http://cloud.steampowered.com/ugc/920118814736634899/2AD6C7640F0EA99913E9081B32EDB3A377DFF4E5/
Knocking down my top score should be easy since I quit when I realized how damn late it was.