It's just fucking around for fun.
Sniper perks are designed specifically for initiating combat with a special attack from Stealth.
Thermodynamic Destabilization + Aimed Shot is simply pointless cause most mobs will die from an Aimed Shot attack anyway.
There are not enough skill points to maximize both Sniper and Metathermics potential therefore the most likely result would be a
retarded mediocre build.
I'm not saying that it would not work (even on Domination) but I'm pretty sure it would be frustrating on late game.
I wanted to see
Sweeper suffer through Expedition but now my plan is spoiled